If all you're trying to do is launch a pythonista script you could use something like the launch center pro today widget with an action that launches a pythonista script via callback url.
See this module. This does a little more, but open_finder pops up a dialog, lets you select.
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Ah, that make sense. Problem solved. :)
iBooks' URL scheme accepts iTunes store links, but I'm trying to pass in my own generated ePub. Different job.
Also, you can't just open a link to a file in an external web browser. Launching Safari isn't going to help at all.
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