https://forum.omz-software.com/topic/6017/import-cairo
You won't be able to use pycairo, though there are some ways to wrap cairo for use in pythonista.

The bigger issue is going to be the lack of ffmpeg for creating the videos.

In short, you will not be able to use manim. It might be possible to use some of the manim structures, and then create a pythonista scene that draws it. But that's going to be a lot of work.