@mikael Running scripts in pythonista withot saving a local copy seems possible. StaSh already supports running scripts directly from dropbox, so all needed to do would be implementing something like this for iCloud and working copy. IIRC, working copy contains some sort of WebDAV (or am i wrong?), so we could use this.
Well, this still would not be built-in support for pythonista, but it may be a good alternative.